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Clinical Research


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Undertaking Community Engagement for a Controlled Human Malaria Infection Study in Kenya: Approaches and Lessons Learnt.Mumba N, Njuguna P, Chi P, Marsh V, Awuor E, Hamaluba M, Mauncho C, Mwalukore S, Masha J, Mwangoma M, Kalama B, Alphan H, Wambua J, Bejon P, Kamuya D, Kapulu MC
Front Public Health, (2022). 10:793913

Incidence of chikungunya virus infections among Kenyan children with neurological disease, 2014-2018: A cohort study.Nyamwaya DK, Otiende M, Mwango L, Kariuki SM, Otieno B, Omuoyo DO, Githinji G, Kitsao BS, Karanja HK, Gitonga JN, de Laurent ZR, Davies A, Mwarumba S, Agoti CN, Thumbi SM, Hamaluba MM, Newton CR, Bejon P, Warimwe GM
PLoS Med, (2022). 19:e1003994

HIV virological non-suppression is highly prevalent among 18- to 24-year-old youths on antiretroviral therapy at the Kenyan coast.Nyongesa MK, Mwatasa MH, Kagonya VA, Mwambingu G, Ngetsa C, Newton CRJC, Abubakar A
BMC Infect Dis, (2022). 22:449

Group B streptococcus infection during pregnancy and infancy: estimates of regional and global burden.Goncalves BP, Procter SR, Paul P, Chandna J, Lewin A, Seedat F, Koukounari A, Dangor Z, Leahy S, Santhanam S, John HB, Bramugy J, Bardaji A, Abubakar A, Nasambu C, Libster R, Sanchez Yanotti C, Horvath-Puho E, Sorensen HT, van de Beek D, Bijlsma MW, Gardner WM, Kassebaum N, Trotter C, Bassat Q, Madhi SA, Lambach P, Jit M, Lawn JE, GBS Danish Dutch collaborative group for long term outcomes, GBS Low Middle Income Countries collaborative group for long term outcomes, GBS Scientific Advisory Group epidemiological sub-group, Champs team
Lancet Glob Health, (2022). 10:e807-e819

The burden of neurological impairments and disability in older children measured in disability-adjusted life-years in rural Kenya.Abuga JA, Kariuki SM, Abubakar A, Kinyanjui SM, van Hensbroek MB, Newton CR
PLOS Glob Public Health, (2022). 2:e0000151

The Prevalence of Onchocerciasis-Associated Epilepsy in Mundri West and East Counties, South Sudan: A Door-to-Door Survey.Jada SR, Dusabimana A, Abd-Elfarag G, Okaro S, Brusselaers N, Carter JY, Logora MY, Rovarini JM, Newton CR, Colebunders R
Pathogens, (2022). 11:396

Validity of the SNAP-IV For ADHD Assessment in South African Children With Neurodevelopmental Disorders.Zieff MR, Hoogenhout M, Eastman E, Christ BU, Galvin A, de Menil V, Abubakar A, Newton CR, Robinson E, Donald KA
J Autism Dev Disord, (2022). 53:2851-2862

A Clinical and Physiological Prospective Observational Study on the Management of Pediatric Shock in the Post-Fluid Expansion as Supportive Therapy Trial Era.Obonyo NG, Olupot-Olupot P, Mpoya A, Nteziyaremye J, Chebet M, Uyoga S, Muhindo R, Fanning JP, Shiino K, Chan J, Fraser JF, Maitland K
Pediatr Crit Care Med, (2022). 23:502-513

Low Hemoglobin Levels Are Associated with Reduced Psychomotor and Language Abilities in Young Ugandan Children.Nampijja M, Mutua AM, Elliott AM, Muriuki JM, Abubakar A, Webb EL, Atkinson SH
Nutrients, (2022). 14:1452

The impact of Loa loa microfilaraemia on research subject retention during a whole sporozoite malaria vaccine trial in Equatorial Guinea.Manock SR, Nsue VU, Olotu A, Mpina M, Nyakarungu E, Raso J, Mtoro A, Ondo Mangue ME, Ntutumu Pasialo BE, Nguema R, Riyahi P, Schindler T, Daubenberger C, Church LWP, Billingsley PF, Richie TL, Abdulla S, Hoffman SL
Trans R Soc Trop Med Hyg, (2022). 116:745-749

Sociocultural perspectives on suicidal behaviour at the Coast Region of Kenya: an exploratory qualitative study.Ongeri L, Nyawira M, Kariuki SM, Theuri C, Bitta M, Penninx B, Newton CR, Tijdink J
BMJ Open, (2022). 12:e056640

TRUE-1: Trial of Repurposed Unithiol for snakebite Envenoming phase 1 (safety, tolerability, pharmacokinetics and pharmacodynamics in healthy Kenyan adults).Abouyannis M, FitzGerald R, Ngama M, Mwangudzah H, Nyambura YK, Ngome S, Riako D, Babu L, Lewa F, Else L, Dily Penchala S, Orindi B, Mumba N, Kalama B, Ndungu FM, Adetifa I, Khoo S, Lalloo DG, Casewell NR, Hamaluba M
Wellcome Open Res, (2022). 7:90

Perspectives of key stakeholders on educational experiences of children with autism spectrum disorders at the Kenyan Coast.Abubakar A, Gona JK, Kipkemoi P, Rimba K, Amukambwa D, Newton CRJC
Afr J Disabil, (2022). 11:847

Brief report: Validity and reliability of the Nigerian Autism Screening Questionnaire.Bakare MO, Frazier TW, Karpur A, Abubakar A, Nyongesa MK, Mwangi PM, Dixon P, Khaliq I, Gase NK, Sandstrom J, Okidegbe N, Rosanoff M, Munir KM, Shih A
Autism, (2022). 26:1581-1590

Measurement characteristics and correlates of HIV-related stigma among adults living with HIV: a cross-sectional study from coastal Kenya.Wanjala SW, Nyongesa MK, Mwangi P, Mutua AM, Luchters S, Newton CRJC, Abubakar A
BMJ Open, (2022). 12:e050709

Whole blood versus red cell concentrates for children with severe anaemia: a secondary analysis of the Transfusion and Treatment of African Children (TRACT) trial.George EC, Uyoga S, M'Baya B, Kyeyune Byabazair D, Kiguli S, Olupot-Olupot P, Opoka RO, Chagaluka G, Alaroker F, Williams TN, Bates I, Mbanya D, Gibb DM, Walker AS, Maitland K, Tract trial study group
Lancet Glob Health, (2022). 10:e360-e368

Traumatic experiences assessed with the life events checklist for Kenyan adults.Kwobah EK, Misra S, Ametaj AA, Stevenson A, Stroud RE, Koenen KC, Gelaye B, Kariuki SM, Newton CR, Atwoli L
J Affect Disord, (2022). 303:161-167

Cytomegalovirus viremia predicts post-discharge mortality in Kenyan HIV-exposed uninfected children.Pavlinac P, Singa B, Huang ML, Shrestha L, Li V, Atlas HE, Diakhate MM, Brander R, Meshak L, Bogonko G, Tickell KD, McGrath CJ, Machuara IM, Ounga DO, Berkley J, Richardson BA, John-Stewart G, Walson JL, Slyker J
J Infect Dis, (2022). 226:1519-1527

Measuring psychological distress using the K10 in Kenya.Ongeri L, Ametaj A, Kim H, Stroud RE, Newton CR, Kariuki SM, Atwoli L, Kwobah E, Gelaye B
J Affect Disord, (2022). 303:155-160

A predictive algorithm for identifying children with sickle cell anemia among children admitted to hospital with severe anemia in Africa.Olupot-Olupot P, Connon R, Kiguli S, Opoka RO, Alaroker F, Uyoga S, Nakuya M, Okiror W, Nteziyaremye J, Ssenyondo T, Nabawanuka E, Kayaga J, Williams Mukisa C, Amorut D, Muhindo R, Frost G, Walsh K, Macharia AW, Gibb DM, Walker AS, George EC, Maitland K, Williams TN
Am J Hematol, (2022). 97:527-536