Publications

Biosciences

Kinetics of naturally induced binding and neutralising anti-SARS-CoV-2 antibody levels and potencies among SARS-CoV-2 infected Kenyans with diverse grades of COVID-19 severity: an observational study.Kimotho, J. Sein, Y. Sayed, S. Shah, R. Mwai, K. Saleh, M. Wanjiku, P. Mwacharo, J. Nyagwange, J. Karanja, H. Kutima, B. Gitonga, J. N. Mugo, D. Karanu, A. Moranga, L. Oluoch, V. Shah, J. Mutiso, J. Mburu, A. Nneka, Z. Betti, P. Usyu Mutinda, W. Abdi, A. I. Bejon, P. Ochola-Oyier, L. I. Warimwe, G. M. Nduati, E. W. Ndungu, F. M.
Wellcome Open Res, (2025). 8:350

Linking Cerebral Malaria Pathogenesis to APOE-Mediated Amyloidosis: Observations and Hypothesis.Kioko, M. Mwangi, S. Njunge, J. M. Berkley, J. A. Bejon, P. Abdi, A. I.
Mol Neurobiol, (2025). 62:1720-1725

Malaria Chemotherapeutics What Next for Africa.Ochola, L. Gitaka, J. Kanoi, B. Kimani, C. N. Akala, H. M. Alfred, M. O. Ochola-Oyier, L. I. Ogutu, B.
Advanced Therapeutics, (2025). 8:2400453

Comparative performance of the InBios SCoV-2 Detect (TM) IgG ELISA and the in-house KWTRP ELISA in detecting SARS-CoV-2 spike IgG antibodies in Kenyan populations.Kutima, B. Kagucia, E. W. Mwai, K. Kimani, M. Sigilai, A. Mugo, D. Karanja, H. Gitonga, J. N. Karani, A. Akech, D. Toroitich, M. Karia, B. Tuju, J. Ziraba, A. K. Bigogo, G. Ochieng, C. Onyango, C. Lidechi, S. Munywoki, P. K. Uyoga, S. Adetifa, I. M. O. Oyier, L. I. O. Bejon, P. Scott, J. A. G. Agweyu, A. Warimwe, G. M. Nyagwange, J. Kenya, Sars-CoV-Serology Consortium
Wellcome Open Res, (2024). 9:349

Evaluation of population immunity against SARS-CoV-2 variants, EG.5.1, FY.4, BA.2.86, JN.1, JN.1.4, and KP.3.1.1 using samples from two health demographic surveillance systems in Kenya.Lugano, D. Kutima, B. Kimani, M. Sigilai, A. Gitonga, J. Karani, A. Akech, D. Karia, B. Ziraba, A. K. Maina, A. Lambisia, A. Omuoyo, D. Mugo, D. Lucinde, R. Owuor, S. Konyino, G. Newman, J. Bailey, D. Nduati, E. Githinji, G. Agoti, C. N. Bejon, P. Scott, J. A. G. Agweyu, A. Kagucia, W. Warimwe, G. M. Sande, C. Ochola-Oyier, L. I. Nyagwange, J.
BMC Infect Dis, (2024). 24:1474

Identification of complex Plasmodium falciparum genetic backgrounds circulating in Africa: a multicountry genomic epidemiology analysis.Miotto, O. Amambua-Ngwa, A. Amenga-Etego, L. N. Abdel Hamid, M. M. Adam, I. Aninagyei, E. Apinjoh, T. Awandare, G. A. Bejon, P. Bertin, G. I. Bouyou-Akotet, M. Claessens, A. Conway, D. J. D'Alessandro, U. Diakite, M. Djimde, A. Dondorp, A. M. Duffy, P. Fairhurst, R. M. Fanello, C. I. Ghansah, A. Ishengoma, D. S. Lawniczak, M. Maiga-Ascofare, O. Auburn, S. Rosanas-Urgell, A. Wasakul, V. White, N. F. D. Harrott, A. Almagro-Garcia, J. Pearson, R. D. Goncalves, S. Ariani, C. Bozdech, Z. Hamilton, W. L. Simpson, V. Kwiatkowski, D. P.
Lancet Microbe, (2024). 5:100941

Prospective clinical surveillance for severe acute respiratory illness and COVID-19 vaccine effectiveness in Kenyan hospitals during the COVID-19 pandemic.Lucinde, R. K. Gathuri, H. Isaaka, L. Ogero, M. Mumelo, L. Kimego, D. Mbevi, G. Wanyama, C. Otieno, E. O. Mwakio, S. Saisi, M. Isinde, E. Oginga, I. N. Wachira, A. Manuthu, E. Kariuki, H. Nyikuli, J. Wekesa, C. Otedo, A. Bosire, H. Okoth, S. B. Ongalo, W. Mukabi, D. Lusamba, W. Muthui, B. Adembesa, I. Mithi, C. Sood, M. Ahmed, N. Gituma, B. Giabe, M. Omondi, C. Aman, R. Amoth, P. Kasera, K. Were, F. Nganga, W. Berkley, J. A. Tsofa, B. Mwangangi, J. Bejon, P. Barasa, E. English, M. Scott, J. A. G. Akech, S. Kagucia, E. W. Agweyu, A. Etyang, A. O.
BMC Infect Dis, (2024). 24:1246

ONT sequencing identifies a high prevalence of crt sensitive, triple mutant dhfr and single mutant dhps parasites within an ANC population in Nigeria.Adegbola, A. J. Ndwiga, L. Wamae, K. Osoti, V. Bolaji, O. O. Bejon, P. Ochola-Oyier, L. I.
Front Genet, (2024). 15:1470156

Molecular xenomonitoring reveals Anopheles funestus and An. rivulorum as the primary vectors of lymphatic filariasis in coastal Kenya.Bartilol, B. Babu, L. Garama, K. Karisa, J. Kamau, A. Mwandawiro, C. Wanjiku, C. Mbogo, C. Maia, M. Mwangangi, J. Rono, M. K.
Parasit Vectors, (2024). 17:425

A cross-sectional analysis identifies a low prevalence of Plasmodium ovale species infections in symptomatic and asymptomatic individuals in Kilifi county, Kenya.Akinyi, M. Y. Chifwete, M. Ndwiga, L. Kimenyi, K. M. Osoti, V. Ochola-Oyier, L. I.
Wellcome Open Res, (2024). 7:207

Mosquitocidal efficacy and pharmacokinetics of single-dose ivermectin versus three-day dose regimen for malaria vector control compared with albendazole and no treatment: An open-label randomized controlled trial.Kamau, Y. Tuwei, M. Wanjiku, C. Ominde, K. Ngama, M. Karisa, J. Babu, L. Muturi, M. Mwatasa, M. Adetifa, J. Kern, C. Duthaler, U. Hammann, F. Rabinovich, R. Chaccour, C. Maia, M. F.
Int J Infect Dis, (2024). 148:107236

Antibodies to PfEMP1 and variant surface antigens: Protection after controlled human malaria infection in semi-immune Kenyan adults.Kinyua, A. W. Turner, L. Kimingi, H. W. Mwai, K. Mwikali, K. Andisi, C. Sim, B. K. L. Bejon, P. Kapulu, M. C. Kinyanjui, S. M. Lavstsen, T. Abdi, A. I. Chmi-Sika Study Team
J Infect, (2024). 89:106252

The mRNA content of plasma extracellular vesicles provides a window into molecular processes in the brain during cerebral malaria.Kioko, M. Mwangi, S. Pance, A. Ochola-Oyier, L. I. Kariuki, S. Newton, C. Bejon, P. Rayner, J. C. Abdi, A. I.
Sci Adv, (2024). 10:eadl2256

A retrospective analysis of P. falciparum drug resistance markers detects an early (2016/17) high prevalence of the k13 C469Y mutation in asymptomatic infections in Northern Uganda.Ogwang, R. Osoti, V. Wamae, K. Ndwiga, L. Muteru, K. Ningwa, A. Tuju, J. Kinyanjui, S. Osier, F. Marsh, K. Bejon, P. Idro, R. Ochola-Oyier, L. I.
Antimicrob Agents Chemother, (2024). 68:e0157623

Profiling IgG and IgA antibody responses during vaccination and infection in a high-risk gonorrhoea population.Stejskal, L. Thistlethwaite, A. Ramirez-Bencomo, F. Rashmi, S. Harrison, O. Feavers, I. M. Maiden, M. C. J. Jerse, A. Barnes, G. Chirro, O. Chemweno, J. Nduati, E. Cehovin, A. Tang, C. Sanders, E. J. Derrick, J. P.
Nat Commun, (2024). 15:6712

Utility of MALDI-TOF MS for determination of species identity and blood meal sources of primary malaria vectors on the Kenyan coast.Karisa, J. Ominde, K. Tuwei, M. Bartilol, B. Ondieki, Z. Musani, H. Wanjiku, C. Mwikali, K. Babu, L. Rono, M. Eminov, M. Mbogo, C. Bejon, P. Mwangangi, J. Laroche, M. Maia, M.
Wellcome Open Res, (2024). 8:151

Biomarkers of mortality in adults and adolescents with advanced HIV in sub-Saharan Africa.Riitho, V. Connon, R. Gwela, A. Namusanje, J. Nhema, R. Siika, A. Bwakura-Dangarembizi, M. Musiime, V. Berkley, J. A. Szubert, A. J. Gibb, D. M. Walker, A. S. Klein, N. Prendergast, A. J.
Nat Commun, (2024). 15:5492

Evaluation of copromicroscopy, multiplex-qPCR and antibody serology for monitoring of human ascariasis in endemic settings.Mugo, R. M. Rausch, S. Musimbi, Z. D. Strube, C. Raulf, M. K. Landt, O. Gichuki, P. M. Ebner, F. Mwacharo, J. Odiere, M. R. Ndungu, F. M. Njomo, D. W. Hartmann, S.
PLoS Negl Trop Dis, (2024). 18:e0012279

Barriers and enablers to the effective implementation of omics research in low- and middle-income countries.Nacis, J. S. Kamande, P. Toni, A. T. Mudibo, E. Musyimi, R. Popluechai, S. Dailey-Chwalibog, T. Voskuijl, W. Dable-Tupas, G. Shahid, Asmsb Bascos, N. A. Afroze, F. Chisti, M. J. Singa, B. Ngari, M. Tigoi, C. Mhango, G. Freitag, H. Potani, I. Mukisa, J. Kirolos, A. Mutasa, K. Ouedraogo, L. O. Prentice, A. M. Girma, T. Prendergast, A. J. Njunge, J. Kelly, P. Berkley, J. A. Tickell, K. D. Gonzales, G. B.
Nat Biotechnol, (2024). 42:988-991

Tungiasis among children in Kenya is associated with poor nutrition status, absenteeism, poor school performance and high impact on quality of life.Elson, L. Kamau, C. Koech, S. Muthama, C. Gachomba, G. Sinoti, E. Chondo, E. Mburu, E. Wakio, M. Lore, J. Maia, M. Adetifa, I. Orindi, B. Bejon, P. Fillinger, U.
PLoS Negl Trop Dis, (2024). 18:e0011800