biosciences/Front Immunol

B and T cell responses to pre-erythrocytic R21/Matrix-M and blood-stage RH5.1/Matrix-M malaria vaccines in endemic settings.Bundi, C. K. Munoz, O. Kibwana, E. Bellamy, D. Stockdale, L. Barrett, J. R. McHugh, K. Mtaka, I. Kalinga, W. Kimani, D. Nyamako, L. Keter, K. Ogwang, R. Hill, A. V. S. Bejon, P. Hamaluba, M. Silk, S. E. Minassian, A. M. Draper, S. J. Olotu, A. I. Kapulu, M. C. Ewer, K. J. Nielsen, C. M.
Front Immunol, (2026). 17:1743327

Controlled human malaria infection studies: insights into recent advances and key immunological and ethical implementation lessons.Ogwang, R. Adan, M. Bejon, P. Kapulu, M. C.
Front Immunol, (2025). 16:1672945

R21/Matrix-M malaria vaccine drives diverse immune responses in pre-exposed adults: insights from a phase IIb controlled human malaria infection trial.Kibwana, E. Bundi, C. Kimani, D. Nyamako, L. Keter, K. Mutiso, A. Ogwang, R. Bellamy, D. Rapi, K. Bajer, A. Provstgaard-Morys, S. Stockdale, L. Munoz, O. Datoo, M. S. Lawrie, A. Ramos-Lopez, F. Roberts, R. Hamaluba, M. Hill, A. V. S. Bejon, P. Ewer, K. J. Kapulu, M.
Front Immunol, (2025). 16:1620365

Vaccine-induced responses to R21/Matrix-M - an analysis of samples from a phase 1b age de-escalation, dose-escalation trial.Bundi, C. Bellamy, D. Kibwana, E. Nyamako, L. Ogwang, R. Keter, K. Kimani, D. Salman, A. M. Provstgaard-Morys, S. Stockdale, L. Hill, A. V. S. Bejon, P. Olotu, A. Hamaluba, M. Ewer, K. J. Kapulu, M. C.
Front Immunol, (2025). 16:1620366

Plasmodium falciparum reticulocyte-binding homologues are targets of human inhibitory antibodies and play a role in immune evasion.Reiling, L. Persson, K. E. M. McCallum, F. J. Gicheru, N. Kinyanjui, S. M. Chitnis, C. E. Fowkes, F. J. I. Marsh, K. Beeson, J. G.
Front Immunol, (2025). 16:1532451

Bi-isotype immunoglobulins enhance antibody-mediated neutrophil activity against Plasmodium falciparum parasites.Ogwang, R. Murugu, L. Nkumama, I. N. Nyamako, L. Kai, O. Mwai, K. Murungi, L. Idro, R. Bejon, P. Tuju, J. Kinyanjui, S. M. Osier, F. H. A.
Front Immunol, (2024). 15:1360220

Age-dependent acquisition of IgG antibodies to Shigella serotypes-a retrospective analysis of seroprevalence in Kenyan children with implications for infant vaccination.Kapulu, M. C. Muthumbi, E. Otieno, E. Rossi, O. Ferruzzi, P. Necchi, F. Acquaviva, A. Martin, L. B. Orindi, B. Mwai, K. Kibet, H. Mwanzu, A. Bigogo, G. M. Verani, J. R. Mbae, C. Nyundo, C. Agoti, C. N. Nakakana, U. N. Conti, V. Bejon, P. Kariuki, S. Scott, J. A. G. Micoli, F. Podda, A.
Front Immunol, (2024). 15:1340425

Exposure to common infections may shape basal immunity and potentially HIV-1 acquisition amongst a high-risk population in Coastal Kenya.Fwambah, L. Andisi, C. Streatfield, C. Bromell, R. Hare, J. Esbjornsson, J. Ndung'u, T. Sanders, E. J. Hassan, A. S. Nduati, E.
Front Immunol, (2024). 14:1283559

A metabolic perspective of the neutrophil life cycle: new avenues in immunometabolism.Thind, M. K. Uhlig, H. H. Glogauer, M. Palaniyar, N. Bourdon, C. Gwela, A. Lancioni, C. L. Berkley, J. A. Bandsma, R. H. J. Farooqui, A.
Front Immunol, (2024). 14:1334205

Assessment of a diverse panel of transmitted/founder HIV-1 infectious molecular clones in a luciferase based CD8 T-cell mediated viral inhibition assay.Fernandez, N. Hayes, P. Makinde, J. Hare, J. King, D. Xu, R. Rehawi, O. Mezzell, A. T. Kato, L. Mugaba, S. Serwanga, J. Chemweno, J. Nduati, E. Price, M. A. Osier, F. Ochsenbauer, C. Yue, L. Hunter, E. Gilmour, J. Iavi protocol C investigators
Front Immunol, (2022). 13:1029029

Complement-mediated serum bactericidal activity of antibodies elicited by the Shigella sonnei GMMA vaccine in adults from a shigellosis-endemic country: Exploratory analysis of a Phase 2a randomized study.Kapulu, M. C. Nakakana, U. Scire, A. S. Sarakinou, E. Conti, V. Rossi, O. Acquaviva, A. Necchi, F. Obiero, C. W. Martin, L. B. Bejon, P. Njuguna, P. Micoli, F. Podda, A.
Front Immunol, (2022). 13:971866

Breadth of Antibodies to Plasmodium falciparum Variant Surface Antigens Is Associated With Immunity in a Controlled Human Malaria Infection Study.Kimingi, H. W. Kinyua, A. W. Achieng, N. A. Wambui, K. M. Mwangi, S. Nguti, R. Kivisi, C. A. Jensen, A. T. R. Bejon, P. Kapulu, M. C. Abdi, A. I. Kinyanjui, S. M. Chmi-Sika Study Team
Front Immunol, (2022). 13:894770

Plasmodium falciparum-Specific Memory B-Cell and Antibody Responses Are Associated With Immunity in Children Living in an Endemic Area of Kenya.Jahnmatz, P. Nyabundi, D. Sundling, C. Widman, L. Mwacharo, J. Musyoki, J. Otieno, E. Ahlborg, N. Bejon, P. Ndungu, F. M. Farnert, A.
Front Immunol, (2022). 13:799306

Toll-Like Receptor-Induced Immune Responses During Early Childhood and Their Associations With Clinical Outcomes Following Acute Illness Among Infants in Sub-Saharan Africa.Uebelhoer, L. S. Gwela, A. Thiel, B. Nalukwago, S. Mukisa, J. Lwanga, C. Getonto, J. Nyatichi, E. Dena, G. Makazi, A. Mwaringa, S. Mupere, E. Berkley, J. A. Lancioni, C. L.
Front Immunol, (2022). 12:748996

Chronic Immune Activation and CD4(+) T Cell Lymphopenia in Healthy African Individuals: Perspectives for SARS-CoV-2 Vaccine Efficacy.Wolday, D. Ndungu, F. M. Gomez-Perez, G. P. de Wit, T. F. R.
Front Immunol, (2021). 12:693269

Antibody Responses to Crude Gametocyte Extract Predict Plasmodium falciparum Gametocyte Carriage in Kenya.Omondi, B. R. Muthui, M. K. Muasya, W. I. Orindi, B. Mwakubambanya, R. S. Bousema, T. Drakeley, C. Marsh, K. Bejon, P. Kapulu, M. C.
Front Immunol, (2020). 11:609474

Editorial: Regulation of Immunity to Parasitic Infections Endemic to Africa.Osier, F. Uzonna, J. E.
Front Immunol, (2020). 11:1159

Plasmodium falciparum Merozoite Associated Armadillo Protein (PfMAAP) Is Apically Localized in Free Merozoites and Antibodies Are Associated With Reduced Risk of Malaria.Aniweh, Y. Nyarko, P. B. Charles-Chess, E. Ansah, F. Osier, F. H. A. Quansah, E. Thiam, L. G. Kamuyu, G. Marsh, K. Conway, D. J. Tetteh, K. K. A. Awandare, G. A.
Front Immunol, (2020). 11:505

Corrigendum: Immune Responses to Gametocyte Antigens in a Malaria Endemic Population-The African falciparum Context: A Systematic Review and Meta-Analysis.Muthui, M. K. Kamau, A. Bousema, T. Blagborough, A. M. Bejon, P. Kapulu, M. C.
Front Immunol, (2020). 11:389

Immune Responses to Gametocyte Antigens in a Malaria Endemic Population-The African falciparum Context: A Systematic Review and Meta-Analysis.Muthui, M. K. Kamau, A. Bousema, T. Blagborough, A. M. Bejon, P. Kapulu, M. C.
Front Immunol, (2019). 10:2480