edd/Wellcome Open Res

GRAPEVNE - Graphical Analytical Pipeline Development Environment for Infectious Diseases.Brittain JS, Tsui J, Inward R, Gutierrez B, Mwanyika G, Tegally H, Huynh T, Githinji G, Tessema SK, McCrone JT, Bhatt S, Dasgupta A, Ratcliffe S, Kraemer MUG
Wellcome Open Res, (2025). 10:279

Identification of coxsackievirus A24 variant during an acute hemorrhagic conjunctivitis outbreak in coastal Kenya, 2024.Lambisia AW, Mwita Morobe J, Moraa E, Mwarumba S, Korir FKN, Seif Athman R, Kiptui R, Mbee M, Mugo N, Amoth P, Muange P, Houldcroft JC, Barasa E, Mwangangi J, Githinji G, Holmes CE, Ochola-Oyier LI, Agoti CN
Wellcome Open Res, (2025). 10:28

Comparative performance of the InBios SCoV-2 Detect (TM) IgG ELISA and the in-house KWTRP ELISA in detecting SARS-CoV-2 spike IgG antibodies in Kenyan populations.Kutima B, Kagucia EW, Mwai K, Kimani M, Sigilai A, Mugo D, Karanja H, Gitonga JN, Karani A, Akech D, Toroitich M, Karia B, Tuju J, Ziraba AK, Bigogo G, Ochieng C, Onyango C, Lidechi S, Munywoki PK, Uyoga S, Adetifa IMO, Oyier LIO, Bejon P, Scott JAG, Agweyu A, Warimwe GM, Nyagwange J
Wellcome Open Res, (2024). 9:349

A Phase I trial of Non-invasive�Ventilation�and seizure prophylaxis with levetiracetam In�Children with�Cerebral Malaria Trial (NOVICE-M Trial).Maitland K, Obonyo N, Hamaluba M, Ogoda E, Mogaka C, Williams TN, Newton C, Kariuki SM, Gibb DM, Walker AS, Connon R, George EC
Wellcome Open Res, (2024). 9:281

SEVUparin as a potential Adjunctive Treatment in children with severe malaria: A phase I trial safety and dose finding trial (SEVUSMAART).Maitland K, Hamaluba M, Obonyo N, Oguda E, Mogoka C, Williams TN, Chaponda M, Miti S, Kamavu LK, Jonathan Gwasupika J, Connon R, Gibb DM, Dondorp A, Day N, White N, Walker AS, George EC
Wellcome Open Res, (2023). 8:484

Safety and immunogenicity of ChAdOx1 nCoV-19 (AZD1222) vaccine in adults in Kenya: a phase 1/2 single-blind, randomised controlled trial.Hamaluba M, Sang S, Orindi B, Njau I, Karanja H, Kamau N, Gitonga JN, Mugo D, Wright D, Nyagwange J, Kutima B, Omuoyo D, Mwatasa M, Ngetsa C, Agoti C, Cheruiyot S, Nyaguara A, Munene M, Mturi N, Oloo E, Ochola-Oyier L, Mumba N, Mauncho C, Namayi R, Davies A, Tsofa B, Nduati EW, Aliyan N, Kasera K, Etyang A, Boyd A, Hill A, Gilbert S, Douglas A, Pollard A, Bejon P, Lambe T, Warimwe G
Wellcome Open Res, (2023). 8:182

Universal iron supplementation: the best strategy to tackle childhood anaemia in malaria-endemic countries?.Karthikappallil R, Atkinson SH
Wellcome Open Res, (2023). 8:345

Severe anaemia, iron deficiency, and susceptibility to invasive bacterial infections.Abuga KM, Nairz M, MacLennan CA, Atkinson SH
Wellcome Open Res, (2023). 8:48

Assessment of gestational age at antenatal care visits among Kenyan women to inform delivery of a maternal respiratory syncytial virus (RSV) vaccine in low- and middle-income countries.Nyiro JU, Nyawanda BO, Bukusi E, Mureithi MW, Murunga N, Nokes DJ, Bigogo G, Otieno NA, Opere VA, Ouma A, Pecenka C, Munywoki PK
Wellcome Open Res, (2023). 8:154

A pragmatic randomized controlled trial of standard care versus corticosteroids plus standard care for treatment of pneumonia in adults admitted to Kenyan hospitals (SONIA).Lucinde R, Abdi A, Orindi B, Mwakio S, Gathuri H, Onyango E, Chira S, Ogero M, Isaaka L, Shangala J, Oginga IN, Wachira A, Manuthu E, Kariuki H, Nyikuli J, Wekesa C, Otedo A, Bosire H, Okoth SB, Ongalo W, Mukabi D, Lusamba W, Muthui B, Kirui N, Adembesa I, Mithi C, Sood M, Ahmed N, Gituma B, Ongaki VB, Giabe M, Omondi C, Ombajo LA, Kagucia W, English M, Hamaluba M, Ochola-Oyier LI, Kamuya D, Bejon P, Agweyu A, Akech S, Etyang AO
Wellcome Open Res, (2022). 7:269

Epidemiology of COVID-19 infections on routine polymerase chain reaction (PCR) and serology testing in Coastal Kenya.Nyagwange J, Ndwiga L, Muteru K, Wamae K, Tuju J, Testing Team C, Kutima B, Gitonga J, Karanja H, Mugo D, Kasera K, Amoth P, Murunga N, Babu L, Otieno E, Githinji G, Nokes DJ, Tsofa B, Orindi B, Barasa E, Warimwe G, Agoti CN, Bejon P, Ochola-Oyier LI
Wellcome Open Res, (2022). 7:69

Efficiency of transplacental transfer of respiratory syncytial virus (RSV) specific antibodies among pregnant women in Kenya.Nyiro JU, Bukusi E, Mwaengo D, Nyaguara A, Nyawanda B, Otieno N, Bigogo G, Murunga N, Widdowson MA, Verani JR, Chaves SS, Mwangudza H, Odundo C, Berkley JA, Nokes DJ, Munywoki PK
Wellcome Open Res, (2022). 7:43

TRUE-1: Trial of Repurposed Unithiol for snakebite Envenoming phase 1 (safety, tolerability, pharmacokinetics and pharmacodynamics in healthy Kenyan adults).Abouyannis M, FitzGerald R, Ngama M, Mwangudzah H, Nyambura YK, Ngome S, Riako D, Babu L, Lewa F, Else L, Dily Penchala S, Orindi B, Mumba N, Kalama B, Ndungu FM, Adetifa I, Khoo S, Lalloo DG, Casewell NR, Hamaluba M
Wellcome Open Res, (2022). 7:90

Pharmacokinetics and pharmacodynamics of azithromycin in severe malaria bacterial co-infection in African children (TABS-PKPD): a protocol for a Phase II randomised controlled trial.Olupot-Olupot P, Okiror W, Mnjalla H, Muhindo R, Uyoga S, Mpoya A, Williams TN, terHeine R, Burger DM, Urban B, Connon R, George EC, Gibb DM, Walker AS, Maitland K
Wellcome Open Res, (2021). 6:161

Revealing the extent of the first wave of the COVID-19 pandemic in Kenya based on serological and PCR-test data.Ojal J, Brand SPC, Were V, Okiro EA, Kombe IK, Mburu C, Aziza R, Ogero M, Agweyu A, Warimwe GM, Uyoga S, Adetifa IMO, Scott JAG, Otieno E, Ochola-Oyier LI, Agoti CN, Kasera K, Amoth P, Mwangangi M, Aman R, Ng'ang'a W, Tsofa B, Bejon P, Barasa E, Keeling MJ, Nokes DJ
Wellcome Open Res, (2021). 6:127

Children's Oxygen Administration Strategies And Nutrition Trial (COAST-Nutrition): a protocol for a phase II randomised controlled trial.Kiguli S, Olopot-Olupot P, Alaroker F, Engoru C, Opoka RO, Tagoola A, Hamaluba M, Mnjalla H, Mpoya A, Mogaka C, Nalwanga D, Nabawanuka E, Nokes J, Nyaigoti C, Briend A, van Woensel JBM, Grieve R, Sadique Z, Williams TN, Thomas K, Harrison DA, Rowan K, Maitland K
Wellcome Open Res, (2021). 6:221

Whole genome sequencing of two human rhinovirus A types (A101 and A15) detected in Kenya, 2016-2018.Luka MM, Kamau E, de Laurent ZR, Morobe JM, Alii LK, Nokes DJ, Agoti CN
Wellcome Open Res, (2021). 6:178

Gastroenteritis Rehydration Of children with Severe Acute Malnutrition (GASTROSAM): A Phase II Randomised Controlled trial: Trial Protocol.Olupot-Olupot P, Aloroker F, Mpoya A, Mnjalla H, Passi G, Nakuya M, Houston K, Obonyo N, Hamaluba M, Evans JA, Connon R, George EC, Gibb DM, Maitland K
Wellcome Open Res, (2021). 6:160

An optimization of four SARS-CoV-2 qRT-PCR assays in a Kenyan laboratory to support the national COVID-19 rapid response teams.Mohammed KS, de Laurent ZR, Omuoyo DO, Lewa C, Gicheru E, Cheruiyot R, Bartilol B, Mutua S, Musyoki J, Gumba H, Mwacharo J, Riako D, Mwangi SJ, Gichuki BM, Nyamako L, Karani A, Karanja H, Mugo D, Gitonga JN, Njuguna S, Gumbi W, Tawa B, Tendwa M, Cheruiyot W, Sein Y, Nyambu JK, Patta SO, Thani TS, Maitha EK, Kitole B, Mwakinangu MS, Muslih BS, Otieno JO, Nyiro JU, Kiyuka P, Ndwiga L, Wamae K, Kimani D, Makale J, Morobe JM, Osoti V, Lambisia AW, Odundo C, Mwarumba S, Mutunga M, Bejon P, Tsofa B, Agoti CN, Ochola-Oyier LI
Wellcome Open Res, (2020). 5:162

Haplotype heterogeneity and low linkage disequilibrium reduce reliable prediction of genotypes for the alpha (3.7I) form of alpha-thalassaemia using genome-wide microarray data.Ndila CM, Nyirongo V, Macharia AW, Jeffreys AE, Rowlands K, Hubbart C, Busby GBJ, Band G, Harding RM, Rockett KA, Williams TN, Malaria GENConsortium
Wellcome Open Res, (2020). 5:287