Eunice Kagucia

Assessing the Impact of SARS-CoV-2 Spike Mutations on Antibody Binding: A Comparative Assessment of the Wuhan and JN.1 Variants' Full-Length Spikes in a Multiplex Luminex Assay.Waweru G, Nyakundi R, Kutima B, Owuor S, Konyino G, Gitonga J, Lugano D, Maina A, Musyoki J, Ochola L, Omondi M, Kariuki CK, Ogongo P, Mwachari C, Shee F, Agoti C, Sande C, Uyoga S, Kagucia E, Agweyu A, Bejon P, Scott JAG, Warimwe GM, Ochola-Oyier LI, Nyagwange J
Viruses, (2025). 17:

Modelling the relative contribution of infection, routine vaccination and supplementary immunisation activities to measles seroconversion in Kenyan Children.Mburu C, Ojal J, Selim R, Ombati R, Akech D, Karia B, Tuju J, Sigilai A, Smits G, van Gageldonk P, van der Klis F, Kagucia E, Scott A, Adetifa I, Flasche S
PLoS Comput Biol, (2025). 21:e1013531

Modelling the relative contribution of infection, routine vaccination and supplementary immunisation activities to measles seroconversion in Kenyan Children.Mburu C, Ojal J, Selim R, Ombati R, Akech D, Karia B, Tuju J, Sigilai A, Smits G, Gageldonk PV, Klis FV, Kagucia E, Scott A, Adetifa I, Flasche S
PLoS Comput Biol, (2025). 21:e1013531

The impact of 10-valent pneumococcal conjugate vaccine on the incidence of admissions to hospital with hypoxaemic and non-hypoxaemic pneumonia in Kenyan children.Haeusler IL, Kagucia EW, Bottomley C, Otiende M, Nyiro J, Scott JAG
PLOS Glob Public Health, (2025). 5:e0004888

Lessons learnt during establishment of COVID-19 active vaccine safety surveillance in nine African countries.Cutland CL, Gutu K, Yun JA, Izu A, Mahtab S, Peter J, Ansah NA, Obaro S, Tilahun B, Jambo K, Sow S, Kagucia EW, Chicumbe S, Dlamini T, Browne M, Clothier H, Griffin J, Jiang Y, Lee A, Ghebreab L, Madhi SA, Black SB
Vaccine, (2025). 62:127441

Seroprevalence of Immunoglobulin G against measles and rubella over a 12-year period (2009-2021) in Kilifi, Kenya and the impact of the Measles-Rubella (MR) vaccine campaign of 2016.Mburu CN, Ojal J, Selim R, Ombati R, Akech D, Karia B, Tuju J, Sigilai A, Smits G, van Gageldonk PGM, van der Klis FRM, Flasche S, Kagucia EW, Scott JAG, Adetifa IMO
Vaccine, (2025). 61:127425

Global impact of 10- and 13-valent pneumococcal conjugate vaccines on pneumococcal meningitis in all ages: the PSERENADE project.Yang Y, Knoll MD, Herbert C, Bennett JC, Feikin DR, Quesada MG, Hetrich MK, Zeger SL, Kagucia EW, Xiao M, Cohen AL, van der Linden M, du Plessis M, Yildirim I, Winje BA, Varon E, Valenzuela MT, Valentiner-Branth P, Steens A, Scott JA, Savrasova L, Sanz JC, Khan AS, Oishi K, Nzoyikorera N, Nuorti JP, Mereckiene J, McMahon K, McGeer A, Mackenzie GA, MacDonald L, Ladhani SN, Kristinsson KG, Kleynhans J, Kellner JD, Jayasinghe S, Ho PL, Hilty M, Hammitt LL, Guevara M, Gilkison C, Gierke R, Desmet S, De Wals P, Dagan R, Colzani E, Ciruela P, Chuluunbat U, Chan G, Camilli R, Bruce MG, Brandileone MC, Ampofo K, O'Brien KL, Hayford K
J Infect, (2025). 90:106426

Effect of mass campaigns with full and fractional doses of pneumococcal conjugate vaccine (Pneumosil) on the reduction of nasopharyngeal pneumococcal carriage in Niger: a three-arm, open-label, cluster-randomised trial.Coldiron ME, Soumana I, Baudin E, Langendorf C, Mamiafo Tchoula C, Brah S, Karani A, Gallagher KE, Kagucia EW, Scott JAG, Grais RF
Lancet Infect Dis, (2025). 24:S1473-3099

Comparative performance of the InBios SCoV-2 Detect (TM) IgG ELISA and the in-house KWTRP ELISA in detecting SARS-CoV-2 spike IgG antibodies in Kenyan populations.Kutima B, Kagucia EW, Mwai K, Kimani M, Sigilai A, Mugo D, Karanja H, Gitonga JN, Karani A, Akech D, Toroitich M, Karia B, Tuju J, Ziraba AK, Bigogo G, Ochieng C, Onyango C, Lidechi S, Munywoki PK, Uyoga S, Adetifa IMO, Oyier LIO, Bejon P, Scott JAG, Agweyu A, Warimwe GM, Nyagwange J
Wellcome Open Res, (2024). 9:349

Profile: The Kenya Multi-Site Serosurveillance (KEMIS) collaboration.Kagucia EW, Voller S, Ziraba AK, Bigogo G, Munywoki PK, Makobu K, Nokes DJ, Nyagwange J, Orlendo C, Akech D, Sigilai A, Onyango C, Juma B, Herman-Roloff A, Munyua P, Apondi C, Lidechi S, Audi A, Ouma A, Aol G, Misore T, Nasimiyu C, Onyango D, Lo T, Kasera K, Jalang'o R, Kingwara L, Adetifa I, Etyang AO, Warimwe G, Agweyu A, Scott JAG
Gates Open Res, (2024). 8:60

Evaluation of population immunity against SARS-CoV-2 variants, EG.5.1, FY.4, BA.2.86, JN.1, JN.1.4, and KP.3.1.1 using samples from two health demographic surveillance systems in Kenya.Lugano D, Kutima B, Kimani M, Sigilai A, Gitonga J, Karani A, Akech D, Karia B, Ziraba AK, Maina A, Lambisia A, Omuoyo D, Mugo D, Lucinde R, Owuor S, Konyino G, Newman J, Bailey D, Nduati E, Githinji G, Agoti CN, Bejon P, Scott JAG, Agweyu A, Kagucia W, Warimwe GM, Sande C, Ochola-Oyier LI, Nyagwange J
BMC Infect Dis, (2024). 24:1474

Global impact of ten-valent and 13-valent pneumococcal conjugate vaccines on invasive pneumococcal disease in all ages (the PSERENADE project): a global surveillance analysis.Bennett JC, Deloria Knoll M, Kagucia EW, Garcia Quesada M, Zeger SL, Hetrich MK, Yang Y, Herbert C, Ogyu A, Cohen AL, Yildirim I, Winje BA, von Gottberg A, Viriot D, van der Linden M, Valentiner-Branth P, Suga S, Steens A, Skoczynska A, Sinkovec Zorko N, Scott JA, Savulescu C, Savrasova L, Sanz JC, Russell F, Ricketson LJ, Puentes R, Nuorti JP, Mereckiene J, McMahon K, McGeer A, Mad'arova L, Mackenzie GA, MacDonald L, Lepp T, Ladhani SN, Kristinsson KG, Kozakova J, Klein NP, Jayasinghe S, Ho PL, Hilty M, Heyderman RS, Hasanuzzaman M, Hammitt LL, Guevara M, Grgic-Vitek M, Gierke R, Georgakopoulou T, Galloway Y, Diawara I, Desmet S, De Wals P, Dagan R, Colzani E, Cohen C, Ciruela P, Chuluunbat U, Chan G, Camilli R, Bruce MG, Brandileone MC, Bigogo G, Ampofo K, O'Brien KL, Feikin DR, Hayford K, Pserenade Team
Lancet Infect Dis, (2024). 25:457-470

Prospective clinical surveillance for severe acute respiratory illness and COVID-19 vaccine effectiveness in Kenyan hospitals during the COVID-19 pandemic.Lucinde RK, Gathuri H, Isaaka L, Ogero M, Mumelo L, Kimego D, Mbevi G, Wanyama C, Otieno EO, Mwakio S, Saisi M, Isinde E, Oginga IN, Wachira A, Manuthu E, Kariuki H, Nyikuli J, Wekesa C, Otedo A, Bosire H, Okoth SB, Ongalo W, Mukabi D, Lusamba W, Muthui B, Adembesa I, Mithi C, Sood M, Ahmed N, Gituma B, Giabe M, Omondi C, Aman R, Amoth P, Kasera K, Were F, Nganga W, Berkley JA, Tsofa B, Mwangangi J, Bejon P, Barasa E, English M, Scott JAG, Akech S, Kagucia EW, Agweyu A, Etyang AO
BMC Infect Dis, (2024). 24:1246

Challenges and Approaches to Establishing Multi-Pathogen Serosurveillance: Findings from the 2023 Serosurveillance Summit.Carcelen AC, Kong AC, Takahashi S, Hegde S, Jaenisch T, Chu M, Rochford R, Kostandova N, Gurley ES, Wesolowski A, Azman AS, van der Klis FRM, den Hartog G, Drakeley C, Heaney CD, Winter AK, Salje H, Rodriguez-Barraquer I, Leung DT, Njenga SM, Kagucia EW, Jambo KC, Wolter N, Charles RC, Saboy�-D�az MI, Martin DL, Moss WJ
Am J Trop Med Hyg, (2024). 111:1145-1152

Profile: The Kenya Multi-Site Serosurveillance (KEMIS) collaboration .Kagucia EW, Voller S, Ziraba AK, Bigogo G, Munywoki PK, Makobu K, Nokes DJ, Nyagwange J, Orlendo C, Akech D, Sigilai A, Onyango C, Juma B, Herman-Roloff A, Munyua P, Apondi C, Lidechi S, Audi A, Ouma A, Aol G, Misore T, Nasimiyu C, Onyango D, Lo T, Kasera K, Jalang'o R, Kingwara L, Adetifa I, Etyang AO, Warimwe G, Agweyu A, Scott JAG
Gates Open Res, (2024). 8:

Impact of COVID-19 on mortality in coastal Kenya: a longitudinal open cohort study.Otiende M, Nyaguara A, Bottomley C, Walumbe D, Mochamah G, Amadi D, Nyundo C, Kagucia EW, Etyang AO, Adetifa IMO, Brand SPC, Maitha E, Chondo E, Nzomo E, Aman R, Mwangangi M, Amoth P, Kasera K, Ng'ang'a W, Barasa E, Tsofa B, Mwangangi J, Bejon P, Agweyu A, Williams TN, Scott JAG
Nat Commun, (2023). 14:6879

Symptom prevalence and secondary attack rate of SARS-CoV-2 in rural Kenyan households: A prospective cohort study.Gallagher KE, Nyiro J, Agoti CN, Maitha E, Nyagwange J, Karani A, Bottomley C, Murunga N, Githinji G, Mutunga M, Ochola-Oyier LI, Kombe I, Nyaguara A, Kagucia EW, Warimwe G, Agweyu A, Tsofa B, Bejon P, Scott JAG, Nokes DJ
Influenza Other Respir Viruses, (2023). 17:e13185

SARS-CoV-2 seroprevalence and implications for population immunity: Evidence from two Health and Demographic Surveillance System sites in Kenya, February-December 2022.Kagucia EW, Ziraba AK, Nyagwange J, Kutima B, Kimani M, Akech D, Ng'oda M, Sigilai A, Mugo D, Karanja H, Gitonga J, Karani A, Toroitich M, Karia B, Otiende M, Njeri A, Aman R, Amoth P, Mwangangi M, Kasera K, Ng'ang'a W, Voller S, Ochola-Oyier LI, Bottomley C, Nyaguara A, Munywoki PK, Bigogo G, Maitha E, Uyoga S, Gallagher KE, Etyang AO, Barasa E, Mwangangi J, Bejon P, Adetifa IMO, Warimwe GM, Scott JAG, Agweyu A
Influenza Other Respir Viruses, (2023). 17:e13173

Mortality associated with third-generation cephalosporin resistance in Enterobacterales bloodstream infections at eight sub-Saharan African hospitals (MBIRA): a prospective cohort study.Aiken AM, Rehman AM, de Kraker MEA, Madrid L, Kebede M, Labi AK, Obeng-Nkrumah N, Nyamwaya B, Kagucia E, Cocker D, Kawaza K, Lester R, Iregbu KC, Medugu N, Nwajiobi-Princewill PI, Dramowski A, Sonda T, Hemed A, Fwoloshi S, Ojok D, Scott JAG, Whitelaw A
Lancet Infect Dis, (2023). S1473-3099:00233-5

Population immunity to pneumococcal serotypes in Kilifi, Kenya, before and 6 years after the introduction of PCV10 with a catch-up campaign: an observational study of cross-sectional serosurveys.Gallagher KE, Adetifa IMO, Mburu C, Bottomley C, Akech D, Karani A, Pearce E, Wang Y, Kagucia EW, Goldblatt D, Hammitt LL, Scott JAG
Lancet Infect Dis, (2023). S1473-3099:00206-2