Melissa Kapulu

R21/Matrix-M malaria vaccine drives diverse immune responses in pre-exposed adults: insights from a phase IIb controlled human malaria infection trial.Kibwana, E. Bundi, C. Kimani, D. Nyamako, L. Keter, K. Mutiso, A. Ogwang, R. Bellamy, D. Rapi, K. Bajer, A. Provstgaard-Morys, S. Stockdale, L. Munoz, O. Datoo, M. S. Lawrie, A. Ramos-Lopez, F. Roberts, R. Hamaluba, M. Hill, A. V. S. Bejon, P. Ewer, K. J. Kapulu, M.
Front Immunol, (2025). 16:1620365

Reversible host cell surface remodelling limits immune recognition and maximizes survival of Plasmodium falciparum gametocytes.Ngotho, P. Dantzler Press, K. Peedell, M. Muasya, W. Omondi, B. R. Otoboh, S. E. Gomez, J. Coronado, L. Seydel, K. B. Kapulu, M. Laufer, M. Taylor, T. Bousema, T. Marti, M.
PLoS Pathog, (2025). 21:e1013110

Protein-specific immune response elicited by the Shigella sonnei 1790GAHB GMMA-based candidate vaccine in adults with varying exposure to Shigella.Randall, A. Z. Conti, V. Nakakana, U. Liang, X. Teng, A. A. Di Pasquale, A. L. Kapulu, M. Frenck, R, Jr. Launay, O. Ferruzzi, P. Scire, A. S. Marchetti, E. Obiero, C. Pablo, J. V. Edgar, J. Bejon, P. Shandling, A. D. Campo, J. J. Yee, A. Martin, L. B. Podda, A. Micoli, F.
mSphere, (2025). 10:e0105724

Reversible host cell surface remodelling limits immune recognition and maximizes transmission of Plasmodium falciparum gametocytes.Ngotho, P. Press, K. D. Peedell, M. Muasya, W. Omondi, B. R. Otoboh, S. E. Seydel, K. B. Kapulu, M. Laufer, M. Taylor, T. Bousema, T. Marti, M.
bioRxiv, (2024). :

Fourth Controlled Human Infection Model (CHIM) meeting - CHIMs in endemic countries, May 22-23, 2023.Kapulu, M. Manda-Taylor, L. Balasingam, S. Means, G. Ayiro Malungu, M. Bejon, P. Chi, P. C. Chiu, C. Church, E. C. Correa-Oliveira, R. Day, N. Durbin, A. Egesa, M. Emerson, C. Jambo, K. Mathur, R. Metzger, W. Mumba, N. Nazziwa, W. Olotu, A. Rodgers, J. Sinyiza, F. Talaat, K. Kamerling, I. Weller, C. Baay, M. Neels, P.
Biologicals, (2024). 85:101747

Fourth Controlled Human Infection Model (CHIM) meeting, CHIM regulatory issues, May 24, 2023.Cavaleri, M. Kaslow, D. Boateng, E. Chen, W. H. Chiu, C. Choy, R. K. M. Correa-Oliveira, R. Durbin, A. Egesa, M. Gibani, M. Kapulu, M. Katindi, M. Olotu, A. Pongsuwan, P. Simuyandi, M. Speder, B. Talaat, K. R. Weller, C. Wills, B. Baay, M. Balasingam, S. Olesen, O. F. Neels, P.
Biologicals, (2024). 85:101745

Controlled Human Malaria Infection Studies in Africa-Past, Present, and Future.Kibwana, E. Kapulu, M. Bejon, P.
Curr Top Microbiol Immunol, (2024). 445:337-365

Safety and immunogenicity of varied doses of R21/Matrix-M vaccine at three years follow-up: A phase 1b age de-escalation, dose-escalation trial in adults, children, and infants in Kilifi-Kenya.Sang, S. Datoo, M. S. Otieno, E. Muiruri, C. Bellamy, D. Gathuri, E. Ngoto, O. Musembi, J. Provstgaard-Morys, S. Stockdale, L. Aboagye, J. Woods, D. Lawrie, A. Roberts, R. Keter, K. Kimani, D. Ndungu, F. Kapulu, M. Njau, I. Orindi, B. Ewer, K. J. Hill, A. V. S. Bejon, P. Hamaluba, M.
Wellcome Open Res, (2023). 8:450

Where do those data go? Reuse of screening results from clinical trials to estimate population prevalence of HBV infection in adults in Kilifi, Kenya.Downs, L. O. Campbell, C. Abouyannis, M. Otiende, M. Kapulu, M. Obiero, C. W. Hamaluba, M. Ngetsa, C. Andersson, M. I. Githinji, G. Warimwe, G. Baisley, K. Scott, J. A. G. Matthews, P. C. Etyang, A.
J Virus Erad, (2023). 9:100355

Sporozoite immunization: innovative translational science to support the fight against malaria.Richie, T. L. Church, L. W. P. Murshedkar, T. Billingsley, P. F. James, E. R. Chen, M. C. Abebe, Y. K, C. N. Chakravarty, S. Dolberg, D. Healy, S. A. Diawara, H. Sissoko, M. S. Sagara, I. Cook, D. M. Epstein, J. E. Mordmuller, B. Kapulu, M. Kreidenweiss, A. Franke-Fayard, B. Agnandji, S. T. Lopez Mikue, M. A. McCall, M. B. B. Steinhardt, L. Oneko, M. Olotu, A. Vaughan, A. M. Kublin, J. G. Murphy, S. C. Jongo, S. Tanner, M. Sirima, S. B. Laurens, M. B. Daubenberger, C. Silva, J. C. Lyke, K. E. Janse, C. J. Roestenberg, M. Sauerwein, R. W. Abdulla, S. Dicko, A. Kappe, S. H. I. Sim, B. K. L. Duffy, P. E. Kremsner, P. G. Hoffman, S. L.
Expert Rev Vaccines, (2023). 22:964-1007

Ethical considerations around volunteer payments in a malaria human infection study in Kenya: an embedded empirical ethics study.Chi, P. C. Owino, E. A. Jao, I. Bejon, P. Kapulu, M. Marsh, V. Kamuya, D.
BMC Med Ethics, (2022). 23:46

Ethics review of COVID-19 human challenge studies: A joint HRA/WHO workshop.Williams, E. Craig, K. Chiu, C. Davies, H. Ellis, S. Emerson, C. Jamrozik, E. Jefford, M. Kang, G. Kapulu, M. Kolstoe, S. E. Littler, K. Lockett, A. Elena, Rey Messer, J. McShane, H. Saenz, C. Selgelid, M. J. Shah, S. Smith, P. G. Yamazaki, N.
Vaccine, (2022). 40:3484-3489

Equity for excellence in academic institutions: a manifesto for change.Wedekind, L. Noe, A. Mokaya, J. Tamandjou, C. Kapulu, M. Ruecker, A. Kestelyn, E. Zimba, M. Khatamzas, E. Eziefula, A. C. Mackintosh, C. L. Nascimento, R. Ariana, P. Best, D. Gibbs, E. Dunachie, S. Hadley, G. Ravenswood, H. Young, B. Kamau, C. Marsh, K. McShane, H. Hale, R. McPhilbin, E. Ovseiko, P. V. Oxford Equity in Academia, consortium Surender, R. Worland, C. White, L. J. Matthews, P. C.
Wellcome Open Res, (2021). 6:142

Understanding the benefits and burdens associated with a malaria human infection study in Kenya: experiences of study volunteers and other stakeholders.Chi, P. C. Owino, E. A. Jao, I. Olewe, F. Ogutu, B. Bejon, P. Kapulu, M. Kamuya, D. Marsh, V. Chmi-Sika Study Team
Trials, (2021). 22:494

Engagement of ethics and regulatory authorities on human infection studies: Proceedings of an engagement workshop in Zambia.Kunda-Ng'andu, E. M. Simuyandi, M. Kapulu, M. Chirwa-Chobe, M. Mwanyungwi-Chinganya, H. Mwale, S. Chilengi, R. Sharma, A.
Wellcome Open Res, (2021). 6:31

Key criteria for the ethical acceptability of COVID-19 human challenge studies: Report of a WHO Working Group.Jamrozik, E. Littler, K. Bull, S. Emerson, C. Kang, G. Kapulu, M. Rey, E. Saenz, C. Shah, S. Smith, P. G. Upshur, R. Weijer, C. Selgelid, M. J. W. H. O. Working Group for Guidance on Human Challenge Studies in COVID
Vaccine, (2021). 39:633-640

Deliberately infecting healthy volunteers with malaria parasites: Perceptions and experiences of participants and other stakeholders in a Kenyan-based malaria infection study.Jao, I. Marsh, V. Che Chi, P. Kapulu, M. Hamaluba, M. Molyneux, S. Bejon, P. Kamuya, D.
Bioethics, (2020). 34:819-832

Author Correction: The temporal dynamics and infectiousness of subpatent Plasmodium falciparum infections in relation to parasite density.Slater, H. C. Ross, A. Felger, I. Hofmann, N. E. Robinson, L. Cook, J. Goncalves, B. P. Bjorkman, A. Ouedraogo, A. L. Morris, U. Msellem, M. Koepfli, C. Mueller, I. Tadesse, F. Gadisa, E. Das, S. Domingo, G. Kapulu, M. Midega, J. Owusu-Agyei, S. Nabet, C. Piarroux, R. Doumbo, O. Doumbo, S. N. Koram, K. Lucchi, N. Udhayakumar, V. Mosha, J. Tiono, A. Chandramohan, D. Gosling, R. Mwingira, F. Sauerwein, R. Paul, R. Riley, E. M. White, N. J. Nosten, F. Imwong, M. Bousema, T. Drakeley, C. Okell, L. C.
Nat Commun, (2019). 10:2644

Correction to: Detection of Plasmodium falciparum infected Anopheles gambiae using near-infrared spectroscopy.Maia, M. F. Kapulu, M. Muthui, M. Wagah, M. G. Ferguson, H. M. Dowell, F. E. Baldini, F. Ranford-Cartwright, L.
Malar J, (2019). 18:137

The temporal dynamics and infectiousness of subpatent Plasmodium falciparum infections in relation to parasite density.Slater, H. C. Ross, A. Felger, I. Hofmann, N. E. Robinson, L. Cook, J. Goncalves, B. P. Bjorkman, A. Ouedraogo, A. L. Morris, U. Msellem, M. Koepfli, C. Mueller, I. Tadesse, F. Gadisa, E. Das, S. Domingo, G. Kapulu, M. Midega, J. Owusu-Agyei, S. Nabet, C. Piarroux, R. Doumbo, O. Doumbo, S. N. Koram, K. Lucchi, N. Udhayakumar, V. Mosha, J. Tiono, A. Chandramohan, D. Gosling, R. Mwingira, F. Sauerwein, R. Paul, R. Riley, E. M. White, N. J. Nosten, F. Imwong, M. Bousema, T. Drakeley, C. Okell, L. C.
Nat Commun, (2019). 10:1433