0709 203000 - Nairobi 0709 983000 - Kilifi
0709 203000 - NRB 0709 983000 - Kilifi
0709 203000 - NRB | 0709 983000 - Kilifi

Abstract

Hepatitis B Core-Related Antigen Point-of-Care Tests as a Risk Stratification Tool for Treatment Eligibility: Experience From Kenya

Downs LO, Okanda D, Chirro O, Zaharani M, Safari B, Aliyan N, Andersson MI, Tanaka Y, Etyang AO, Shimakawa Y, Githinji G, Matthews PC
Open Forum Infect Dis. 2025;12

Permenent descriptor
https://doi.org/10.1093/ofid/ofaf125


We undertook a point-of-care test for hepatitis B core-related antigen in adults with hepatitis B virus in Kilifi, Kenya. A positive test identified all individuals with a hepatitis B viral load >200 000 IU/mL and who were hepatitis B e antigen positive. It also correlated with a higher alanine aminotransferase (ALT) level (P = .03), raised aspartate transaminase-to-platelet ratio index (APRI) (P < .001), and higher elastography scores (P = .03).